ULTIMATE EDITION
Minimal Downtime.
Little To No Pain.
The World’s 1st FDA-Approved Pulsed Wave and Continuous Wave Radio Frequency Microneedling System
Minimal Downtime.
TREATS MELASMA
MINIMIZES WRINKLES
TREATS PIH
SKIN REJUVENATION
TREATS REDNESS
TREATS ROSACEA
MINIMISES PORES
REDUCES STRETCH MARKS
LIFTS & TIGHTENS
TREATS ACNE SCARS
TREATS ACNE
PROMOTE SCALP CIRCULATION
A New Paradigm Approach To Radio Frequency Microneedling
The world's first and only treatment of its kind featuring both scientifically advanced
Sylfirm X Ultimate Edition dual wave radio frequency microneedling device and
Exosome Technology* to supercharge and X-Cellerate treatment results.
Introducing A Recommended Product For
Combine To Maximize The Results
The Next Small Thing…
Nanoparticles Offering a New Future
Exosome Regenerative Complex
For Skin
EXO Balm
Exosome Regenerative Complex+
For Skin & Scalp
Science &
Technology
What are Exosomes?
BENEV Exosome treatments are based on the most cutting edge scientific biotech breakthrough for skin rejuvenation and regeneration. Exosomes are responsible for cell to cell communication and for facilitating the exchange of RNA and other important proteins between cells (e.g. fibroblasts, keratinocytes, immune cells, etc.), in addition to transferring numerous growth factors and cytokines and genetic materials that have shown signs of tissue repair and improving skin cells. These data coding avatars have been harnessed for our new line of exosome products to promote a more radiant youthful appearance.
IN VIVO TESTING
Exosomes are nano-sized vesicles (30–200 nm) constantly released by almost all cells. The ability of exosomes to travel between cells and deliver their cargo, which includes lipids, proteins, and nucleic acids, makes them an appealing cell-free therapy option to treat multiple diseases. Here, we investigated for the first time whether human adipose tissue-derived mesenchymal stem cell-derived exosomes can ameliorate atopic dermatitis (AD) in an in vivo mouse model. When injected either intravenously (IV) or subcutaneously (SC) into NC/Nga mice treated with house dust mite antigens, ERC-exosomes were found to reduce pathological symptoms such as clinical score, the levels of serum IgE, the number of eosinophils in blood, and the infiltration of mast cells, CD86+, and CD206+ cells in skin lesions. ERC-exosomes also significantly reduced mRNA expression of various inflammatory cytokines such as interleukin (IL)-4, IL-23, IL-31, and tumor necrosis factor (TNF-) in AD skin lesions of Nc/Nga mice. Taken together, these results suggest that ERC-exosomes can be a novel promising cell-free therapeutic modality for AD treatment. (Byong Seung Cho, Jin Ock Kim, Dae Hyun Ha and Yong Weon – Stem Cell Research Therapy, BioMedCentral.com)
Before & After Treatment
